This page is also available in: Srpski Srpski, Italiano Italiano, Lietuviškai Lietuviškai, български български, Magyar Magyar, Español Español

Human Whole Genome Sequencing identifies at one time the individual genetic variations and offers relevant insights on family history and inherited diseases.

Detecting genome wide genetic variations and susceptibility genes is one of the most important approaches of Precision Medicine.

 

Whole Genome Sequencing (also known as WGS or entire genome sequencing) is the process of determining the complete DNA sequence of an organism’s genome at a single time. In other words, Whole Genome Sequencing is the mapping out of a person’s unique DNA.

There is no more extensive analysis that can be performed then Whole Genome Sequencing (WGS) testing. Whole Genome Sequencing Analysis is, as of today, the state-of-the-art technology to decrypt and know an individual in a Single Essay.

The very first human genome was completed in 2003 as part of the Human Genome Project , which was formally started in 1990.

Recent fast developments in DNA sequencing technologies have dramatically cut both the cost and the time required to sequence a human genome making possible the era of personalized human genomics. Furthermore, combined with the advanced understanding of genes and disease, the whole genome sequencing is set to change current clinical practice by enabling more accurate and sophisticated genetic analysis. It can also be applied to research to provide information on cancer and disease associated mutations.

 

What is DNA sequencing?

Sequencing DNA means determining the order of the four chemical building blocks, called “bases” that make up the DNA molecule. The sequence tells scientists the kind of genetic information that is carried in a particular DNA segment.

In the DNA double helix, the four chemical bases always bond with the same partner to form “base pairs.” Adenine (A) always pairs with thymine (T); cytosine (C) always pairs with guanine (G). This pairing is the basis for the mechanism by which DNA molecules are copied when cells divide, and the pairing also underlies the methods by which most DNA sequencing experiments are done. The human genome contains about 3 billion base pairs that spell out the instructions for making and maintaining a human being.

The method using Next Generation Sequencing (NGS) technology produces large volumes of data in a short amount of time and therefore is designed to empower healthcare professionals and patients with quality sequencing data at fast turnaround times.

Sequencing Whole Genome helps people improve their health by giving relevant insights into family history, lifestyle and allows to understand inherited diseases risks. Learning if they are a carrier of a genetic condition and what they could pass on to their children is an information of most importance.

Today, Whole Genome Sequencing is becoming a new way to diagnose diseases or disorders that were undiagnosed using traditional tests.

Genoma Swiss Biotechnology provides accessible and affordable genetic information towards a proactive approach to health leading transformative research and translating it into tangible benefits for society.